"Metabolomics" resources

Metabolomics presents challenges from sample introduction to the analytical methods used, and the data reduction required to interpret the results. No single analytical technique can be used for complete characterization of the metabolome, and no metabolome has ever been completely characterized. Despite these challenges, LECO’s just-in-time derivatizer coupled with the Gas Chromatography Mass Spectrometers (GC-MS) provides an established method to introduce samples into the GC-MS and analyze the primary metabolome, whereas other techniques simply investigate the secondary and tertiary metabolites. One of the principal challenges in metabolomics is the detection and identification of unknowns; you need to know what else is in your sample to successfully characterize it, and our GC-MS solutions give you a clear advantage. Our solutions have a robust automated derivatization and sample introductory method, separation, accuracy, resolving power, deconvolution, and speed to characterize the most complex metabolite profiles.
65 results
SS-ASMS20-LPSS-002 Tile-based Fisher ratio (F-ratio) analysis is used to discover and quantify metabolites in Argentinian pacu fish, using data collected by comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GCxGC-TOFMS) ...
JH-ISCC13-LPSS-109 Rodent liver samples were analyzed to create a standardized GCxGC method and software reference.
Vladimir Tolstikov, PhD, from Eli Lilly discusses utilizing High-Resolution Gas Chromatography Mass Spectrometry in Metabolomics analyses. Accompanying slides are available.
Vladimir Tolstikov, PhD, from Eli Lilly discusses utilizing High-Resolution Gas Chromatography Mass Spectrometry in Metabolomics analyses.
DA-PCON15-LPSS-165
203-821-561 An Online Guide for Optimizing Comprehensive Two Dimensional GC Separations